ABOUT METRA
The biology is well-mapped. The studies exist. The dosing is established. What's missing is someone willing to put it on your kitchen counter every morning.
597 RANDOMIZED CONTROLLED TRIALS · 4 COMPOUNDS · ONE SYSTEM
WHY METRA EXISTS
The science is settled. Berberine activates AMPK. Soluble fiber blunts post-meal glucose spikes. Specific bacterial strains rebuild the gut barrier. Creatine preserves lean muscle. None of this is contested in the literature.
What's missing isn't evidence. It's assembly.
Your doctor hands you a goal — bring your A1C down — and no protocol. The supplement aisle hands you five hundred bottles and no guide. Brands with hundred-product catalogs sell you encyclopedias instead of routines, leaving the curation work to you. PubMed, helpful but unfiltered, hands you twelve thousand papers and no priority order.
Five disconnected fights. None of them yours to fight alone.
Metra is the assembly. Three or four compounds, each clinically dosed, each peer-reviewed, each working a different lever on the same metabolic cascade. Take the system. The biology does the rest.
THE INSIGHT
METRA DAILY · THE METABOLIC SYSTEM · EST. 2025
WHAT WE ASSEMBLED
Four compounds. Four levers. One pathway. The biology of metabolic health is a cascade — one mechanism unlocks the next. We built around all four.
BERBERINE 500MG
Activates AMPK — the cellular energy sensor that controls glucose uptake, fatty acid oxidation, and insulin sensitivity. The same metabolic switch metformin pulls.
PSYLLIUM FIBER 5G
Forms a viscous gel in the small intestine, slowing the absorption of glucose into the bloodstream. Blunts the post-meal spike before it starts.
13-STRAIN PROBIOTIC 30B CFU
Restores gut barrier integrity. The strains feed on the fiber, produce short-chain fatty acids, and signal through the vagus nerve to regulate appetite and inflammation.
CREATINE 5G
Preserves lean muscle under any metabolic protocol that creates a caloric deficit. Replenishes ATP. Crosses the blood-brain barrier. The most-studied performance compound in nutrition.
THE EVIDENCE
RANDOMIZED CONTROLLED TRIALS
ACROSS THE FOUR COMPOUNDS
IN THE METRA SYSTEM.
All counts pulled from PubMed (April 2026). Filtered to randomized controlled trials, peer-reviewed and replicable.
500 MG · 60 CAPSULES
MECHANISM
Activates AMPK — the same metabolic switch metformin pulls. Influences glucose uptake, lipid metabolism, and mitochondrial biogenesis.
LANDMARK CITATION
Zhang Y. et al., J Clin Endocrinol Metab, 2008. RCT in 116 type-2 diabetics, three months. HbA1c and fasting glucose reductions statistically comparable to metformin.
5G · MONOHYDRATE + ELECTROLYTES
MECHANISM
Replenishes ATP. Preserves lean muscle under any metabolic protocol that creates a caloric deficit. Crosses the blood-brain barrier.
LANDMARK CITATION
International Society of Sports Nutrition position stand: creatine monohydrate is the most extensively studied and effective ergogenic supplement, with a strong safety record across decades of trials.
30 BILLION CFU · 13 STRAINS
MECHANISM
Restores gut barrier integrity. Strains drawn from Lactobacillus and Bifidobacterium — the most-researched genera in human gut microbiome science.
LANDMARK CITATION
The gut-metabolic axis: short-chain fatty acid production, vagal signaling, and downstream effects on appetite, inflammation, and glucose handling — documented across thousands of strain-level trials.
5G SOLUBLE · PSYLLIUM + ACACIA
MECHANISM
Forms a viscous gel that slows glucose absorption. Feeds the bacterial colonies the probiotic seeds. Engages GLP-1 signaling pathways.
LANDMARK CITATION
Gibb R.D. et al., Am J Clin Nutr, 2015. Meta-analysis: psyllium improves glycemic control proportional to baseline impairment — the more disrupted the metabolism, the larger the effect.
OUR STANDARDS
Four lines we hold even when nobody is watching the lab. Especially when nobody is watching.
Every compound dosed at the level used in the studies cited on the bottle. If a trial showed effects at 1500 mg, we put 1500 mg in the bottle. Underdosing is the cheapest place to cut and the most common — we don't.
Every milligram of every ingredient is printed on the label. No 'proprietary blend' totals that hide individual doses. If you can't see what's in it, you can't trust what it does.
Every production lot is tested by an independent ISO/IEC 17025–accredited lab for potency, identity, and contaminants — heavy metals, microbials, residual solvents. Certificate of Analysis available on request.
Vegetable cellulose capsules. No fillers, no binders, no coatings, no shortcuts. Manufactured in a U.S. facility that meets the Good Manufacturing Practice requirements of 21 CFR Part 111.
THE PROMISE
We don't ask you to count, track, weigh, or earn it. We don't ask you to give up bread, give up wine, give up dessert, or wake up at 5 AM.
We ask you to take this system every day. Three capsules with breakfast. One scoop in water. The biology does the rest.
If you take it for ninety days and don't feel a difference, we'll refund every dollar. Keep the bottle. Send the email. We'll send the money.
SCIENCE YOU CAN FEEL.
